The article addresses the adoption of polygraph technology and psychological methods in the penal system, highlighting them as effective and human rights-respecting strategies, in accordance with international standards.This approach is aligned with the principles established in international treaties such as the International Covenant on Civil and
The anti-inflammatory effects of depolymerizing microtubule-targeting agents on leukocytes are known for a long time, but the potential involvement of the vascular endothelium and the underlying mechanistic basis is still largely unclear.Using the recently synthesized depolymerizing microtubule-targeting agent pretubulysin, chainsaw file we investi
Abstract Background Multiple myeloma (MM) remains an incurable malignancy, despite the advent of therapies such as proteosome inhibitors (PIs) that disrupt protein homeostasis and induce ER stress.We have pursued inhibition of geranylgeranyl diphosphate synthase (GGDPS) as a novel mechanism by which to target protein homeostasis in MM cells.GGDPS i
Abstract Background A safe and effective technique for anterolateral portal placement in elbow arthroscopy is significant.We compared the outcomes of patients who underwent elbow arthroscopy using different ultrasound-assisted techniques.Methods From May 2016 to June 2021 a retrospective analysis on all patients who underwent elbow arthroscopy in o
The Industry 4.0 concept inception definitively provided a disruptive glimpse in terms of possibilities in a multidisciplinary spectrum.The convergence and synergy from technologies generated quite high expectations.In terms of advancements, the efficiency increase is one of the key factors.Smart factories must be capable of producing more and in a